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Measuring a cumulative effect is seen as the mostmeaningful way of measuring the impact of adversity, rather than the sum of the number of occur-rences of distinctly experienced events

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A clinical trial comparing VTtargets of 3 and 5 mL/kg found the lower value tobe associated with an increase in pro-in? amma-tory cytokines in bronchoalveolar lavage ? uid(Castoldi et al. The potential value of delivering iNOduring HFOV has been highlighted in one trial,in which the proportion of nonresponders waslowest when the two therapies were combined(Kinsella et al. Musclebiopsy is a definitive test to confirm the diagnosis. Giugliani R, Harmatz P, Wraith JE (2007) Management guidelines for mucopolysaccharidosisVI. To burnto death a pig has been recommended by a wise woman of Banffshire as a curefor cattle disease

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17.3 Endotrachealmechanical ventilation andbronchopulmonary dysplasia(BPD) in infants treated withNIMV and NCPAP (Reproducedwith permission from Kugelmanet al. other specialized disci-plines within toxicology also rely heavily on in vitro meth-odologies and computer modeling. In addition, a careful physical examination is needed. The Pawtucket Heart Study showed estimatedmaximal oxygen consumption and self-reportedphysical activity related to blood pressure, BMI, andHDL-C (28). In addi-tion, the letter that appeared in the same edition noted the problems thatChinese foreign exchange students were having when attempting to returnto school after vacations (I.

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